Multiple peer-reviewed publications have consistently demonstrated a set of blood-based protein biomarkers associated with idiopathic pulmonary fibrosis (IPF) disease progression. A set of well-qualified assays suitable for use as prognostic or predictive biomarkers within the context for IPF clinical trials is lacking. In collaboration with the Prognostic Lung Fibrosis Consortium (PROLIFIC), Rules-Based Medicine, a IQVIA Laboratories Company, developed highly optimized and analytically validated blood-based proteomic assays for IPF on the Luminex® multi-analyte profile (MAP), specifically focusing on the most relevant IPF biomarkers related to epithelial damage, fibrosis, inflammation and thrombosis.
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