Immuno-functionality
IQVIA Laboratories brings proven expertise in helping clients assess the immuno-functionality of lead candidates in immuno-oncology, auto-immunity, infection/inflammation, and cell and gene therapy. We help clients assess functionality and reduce risk prior to first-in-human administration. ImmunXperts has assisted drug developers in screening and selecting a wide range of promising candidates, including PD-1/PDL-1 and a wide range of first- and second-generation immune checkpoint inhibitors, advancing approximately 150 programs a year to the next phase of development.
Our immuno-functional services include:
T-cell Assays
Myeloid Cell Assays
Killing Assays
NK Cell Assays
Neutrophil Activation Assays
DC Assays
T-cell Assays
- Mixed Lymphocyte Reaction (MLR) assay
- Antigen-specific (re-)activation assay
- Treg suppression assay
- Exhausted T-cell assays
Myeloid Cell Assays
- Macrophage polarization and suppression assays
- Macrophage activation assay
- Macrophage inflammatory assay
- ADCP assays
Killing Assays
- PBMC killing assay
- Pan T-cell killing assay
- Neutrophil killing assay
NK Cell Assays
- NK activation assay
- ADCC assay
- NK proliferation assay
- Neutrophil assays
Neutrophil Activation Assays
DC Assays
- DC activation/maturation assay
- DCT Flurospot assays (direct ex vivo and enriched)
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