Service
|
Capabilities
|
Location Availability
|
| |
|
USA |
CHINA |
UK |
SINGAPORE |
| Anatomic pathology |
- Fresh tissue and FFPE capabilities
- H&E creation/assessment and digital slide imaging available
- Pathologists onsite
|
✓ |
✓ |
✓ |
✓ |
| Isolations |
- DNA and RNA extraction capabilities from a large spectrum of original material, including FFPE, blood, tissue, cells, plasma, and saliva
|
✓ |
✓ |
✓ |
✓ |
| Whole human genome sequencing |
- Optimized method for FFPE and intact material, using low input and minimal amplification
- Illumina NovaSeq system available
|
✓ |
✓ |
✓ |
|
| DNA exome sequencing |
- Low input procedure optimized for intact and FFPE material
- Flexible hybridization method that allows for use of various standard and customized ROI probe sets
- Illumina NovaSeq system available
|
✓ |
✓ |
|
|
| RNA sequencing |
- Globin removal method to remove globin mRNA from blood
- Library preparation from both intact and degraded RNA from FFPE, blood, tissue, and cells
- Hybridization-based method targeting the human transcriptome
- Poly-A selection method for intact material
- Ribosomal RNA depletion method for degraded and non-coding RNA
- Illumina NovaSeq system available
|
✓ |
✓ |
✓ |
|
| Targeted sequencing |
- Library preparations from RNA/DNA from FFPE, blood, tissues, cells, and plasma
- Hybridization-based methods targeting different panels of interest
- NovaSeq system
|
✓ |
✓ |
✓ |
|
| Thermo Fisher sequencing |
- Manual and Genexus library preparation with various panels
- Customizable with DNA, RNA, or simultaneous profiling available
- Genexus, Ion Chef, S5 XL and PGM Dx platforms available
|
✓ |
✓ |
✓ |
✓ |
| Single cell RNA sequencing |
- Simultaneous analysis of the transcriptome and cell surface proteome
- Various assays including immune repertoire, surface protein profiling, and single-nucleus
- 10X Chromium and Illumina NovaSeq systems available
|
✓ |
|
|
|
| Spatial RNA and protein profiling |
- Customizable, spatially restricted hybridization- and antibody-based RNA and protein quantification, respectively
- Immunofluorescence-guided cell selection and stratification performed by qualified pathologists
- Targeted NanoString nCounter or whole transcriptome (i.e., 18,000+ protein-coding genes) Illumina next-generation sequencing readouts available
|
✓ |
|
|
|
| PCR assays |
- Customizable probe amplification assays for different targets of interest
- Multiple platforms for expression profiling, genotyping, and copy number analysis
- ddPCR and qPCR systems available
- Fluidigm system available at USA site
|
✓ |
✓ |
|
|
| NanoString nCounter panels |
- Probe Hybridization based capture, RNA copies counted by nCounter
- No amplification required
- Customizable
- Up to 800 targets in a single reaction
|
✓ |
✓ |
|
|
| Bioinformatics |
- A range of analyses to support all service lines
- Custom analysis and algorithm development including biostatistics support
- Standard pipeline analysis available globally (including China)
|
Centralized in RTP |
