Assays for Vaccine Development and Testing

At IQVIA Laboratories Vaccines we approach each vaccine program with disciplined agility: scientific excellence and full transparency with the flexibility, ingenuity, and capacity for the quick decision-making needed. Our expertise is built on a foundation of more than 25 years of experience in vaccine efficacy and safety evaluation as a partner to industry leading vaccine manufacturers worldwide. Cutting-edge technology platforms and state-of-the-art laboratories enable us to best develop, qualify, and validate single and multiplex immunological assays and sample testing to support vaccine development.

IQVIA Laboratories Vaccines has seven integrated platforms that help you progress from vaccine development through clinical evaluation. Our focus is on the evaluation of the efficacy of the vaccine — be it in the developmental stages or in clinical immunological responses. Critical reagents and well-established assays are indispensable to the efficient assessment of vaccine candidates. We take pride in our ability to develop innovative and critical reagents in-house. This capacity allows us to scale rapidly and helps control batch-to-batch variations of assay materials — crucial factors in maintaining operational excellence, high quality data, and world class science for our clients.

Our seven platforms include:

• Viral functional assays (link to integrated vaccine platforms page)
• Bacterial functional assays (link to integrated vaccine platforms page)
• Ligand binding assays (link to integrated vaccine platforms page)
• Molecular biology (link to integrated vaccine platforms page)
• Cellular mediated immunology assays (link to integrated vaccine platforms page)
• In vivo models (preclinical) (link to integrated vaccine platforms page)

Automation to execute our assays with each platform also further reduces operator error and increases throughput and assay precision.

Respiratory

• Seasonal and Pandemic Influenza
• Hemophilus influenzae B
• Respiratory Syncytial virus
• Neisseria meningitidis
• Streptococcus pneumoniae
• Bordetella pertussis
• Corynebacterium diphtheriae
• Rhinovirus
• SARS-CoV-1
• SARS-CoV-2
• MERS
• hMPV
• PIV

Enteric

• Escherichia coli
• Shigella spp.
• Clostridium difficile
• Rotavirus
• Salmonella typhimurium

Vector/Zoonotic

• Chikungunya
• Zika
• Dengue
• Ebola
• Malaria
• West Nile
• Tick-borne encephalitis virus
• Yellow Fever
• Nipah

Sexually Transmitted

• Cytomegalovirus
• Herpes simplex virus -1/-2
• Hepatitis A, B, C
• Epstein Barr Virus
• HIV

Other Infectious Diseases

• Human papilloma virus (HPV)
• Adenovirus
• Adeno-associated virus (AAV)
• Measles
• Mumps
• Rubella
• Varicella zoster
• Tetanus
• Staphylococcus aureus
• Streptococcus aga lactiae (GBS)
• Lymphocytic Choriomeningitis Virus (LCMV)
• Mammarenavirus
• Vaccinia, etc. 

Expertise Across All Types of Vaccines

IQVIA Laboratories Vaccines has years of experience in the development of a broad range of vaccine types, including:

Scope of Vaccine Development Services

At every stage of your vaccine development project — whether it is lead finding, target validation, or assessment of efficacy or immunogenicity — a reliable assay is the key to success. Choosing the right set of assays is critical to obtain meaningful data. Several well-designed and optimized assays are required at every stage to generate reliable and predictive data to translate vaccine development programs from early discovery through preclinical, clinical, and regulatory approval.

Using an agile approach, IQVIA Laboratories Vaccines develops and validates a broad range of assays that are robust and reproducible. Employing these methods using our high-throughput automated instruments increases our testing capacity, reduces cost, improves operational efficiency, and delivery times — all custom-tailored to the ideal specifications of your project. This fit-for-purpose approach, acting as an extension of the lab with our platform solutions, allows us to provide a comprehensive, individualized solution. Choose IQVIA Laboratories Vaccines for your vaccine development and baseline vaccine evaluation requirements.