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Validated Models and Assays for CNS Drug Discovery Guide
A guide to model selection and study design
Navigating neuroscience drug discovery requires models that accurately reflect complex human biology and deliver translational insights. This guide provides an overview of validated in vitro and in vivo neuroscience models, assays, and study design considerations across neurodegenerative diseases, neuroinflammation, mental health disorders, pain, injury, ischemia, and rare CNS conditions. Learn how we combine human-relevant in vitro systems, translational pharmacology, advanced biomarkers, and disease-focused expertise to generate evidence that informs confident decision-making from target discovery through candidate selection and validation.
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