Immuno-functionality
IQVIA Laboratories brings proven expertise in helping clients assess the immuno-functionality of lead candidates in immuno-oncology, auto-immunity, infection/inflammation, and cell and gene therapy. We help clients assess functionality and reduce risk prior to first-in-human administration. ImmunXperts has assisted drug developers in screening and selecting a wide range of promising candidates, including PD-1/PDL-1 and a wide range of first- and second-generation immune checkpoint inhibitors, advancing approximately 150 programs a year to the next phase of development.
Our immuno-functional services include:
          T-cell Assays
        
      
          Myeloid Cell Assays
        
      
          Killing Assays
        
      
          NK Cell Assays
        
      
          Neutrophil Activation Assays
        
      
          DC Assays
        
      T-cell Assays
- Mixed Lymphocyte Reaction (MLR) assay
 - Antigen-specific (re-)activation assay
 - Treg suppression assay
 - Exhausted T-cell assays
 
Myeloid Cell Assays
- Macrophage polarization and suppression assays
 - Macrophage activation assay
 - Macrophage inflammatory assay
 - ADCP assays
 
Killing Assays
- PBMC killing assay
 - Pan T-cell killing assay
 - Neutrophil killing assay
 
NK Cell Assays
- NK activation assay
 - ADCC assay
 - NK proliferation assay
 - Neutrophil assays
 
Neutrophil Activation Assays
DC Assays
- DC activation/maturation assay
 - DCT Flurospot assays (direct ex vivo and enriched)
 
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