Next Generation Sequencing Services

With 4 global laboratory locations, IQVIA Laboratories offers a range of next generation sequencing services to support drug discovery, precision medicine, and clinical development. We offer expertise in assay design, development, and validation, plus a translational genomics team comprised of both assay development and bioinformatic scientists, who lead the industry in high-complexity testing and analysis. IQVIA Laboratories offers the following next generation sequencing services:

Service	Capability
Exome Sequencing	Low input procedure optimized for intact and FFPE material Flexible hybridization method that allows for use of various standard and customized ROI probe sets
RNA Sequencing	Capabilities include: Library preparation from both intact and degraded RNA from FFPE, blood, tissue, and cells Techniques include: Hybridization-based method targeting the human transcriptome Poly-A selection method for intact material Ribosomal RNA depletion method for degraded and non-coding RNA
Whole Genome Sequencing	Optimized method for FFPE and intact material, using low input and minimal amplification
DNA and RNA Isolations	DNA and RNA extraction capabilities from a large spectrum of original material, including FFPE, blood, tissue, and cells
ThermoFisher in Ion Torrent AmpliSeq and Oncomine Panels	Library preparation and in Ion Torrent S5 XL or PGM Dx sequencing DNA, RNA, or simultaneous profiling available Customizable Whole Transcriptome panel available
NanoString nCounter Panels	Probe Hybridization based capture, RNA copies counted by nCounter No amplification required Customizable Up to 800 targets in a single reaction
Bioinformatics	Alignment, gene/isoform/junction counts, QC, bacterial/viral detection Gene fusion detection Variant calling HLA allele calling Group comparisons and clinical biostatistics On-site support